diff --git a/configure.ac b/configure.ac
index 6d2cb5583b..eb2b84d0bc 100644
--- a/configure.ac
+++ b/configure.ac
@@ -3314,8 +3314,8 @@ if test "$USE_NGTCP2" = "1" && test "$OPENSSL_ENABLED" = "1" && test "$HAVE_LIBR
   fi
 fi
 
-if test "$USE_NGTCP2" = "1" && test "$OPENSSL_ENABLED" = "1" && test "$OPENSSL_IS_BORINGSSL" != "1" &&
-   test "$OPENSSL_QUIC_API2" != "1"; then
+if test "$USE_NGTCP2" = "1" && test "$OPENSSL_ENABLED" = "1" && test "$HAVE_LIBRESSL" != "1" &&
+   test "$OPENSSL_IS_BORINGSSL" != "1" && test "$OPENSSL_QUIC_API2" != "1"; then
 
   dnl backup the pre-ngtcp2_crypto_quictls variables
   CLEANLDFLAGS="$LDFLAGS"